Osteoarthritis is a degenerative disease of the joints which is caused mainly due to old age. Other factors that play a role are obesity, trauma or disease. What happens is that with age the cartilage of the joint gets damaged, exposing the surfaces of the bone. This exposed surface is vulnerable even to minor insults and is damaged very easily. Whenever this happens, the immune system or the natural defense mechanism of the body gets activated. Immune cells start migrating to this joint and start a process of inflammation. The inflammation is characterized by swelling, redness and pain in the joint.
There is immense pain in the joint and it becomes swollen. That is when Celebrex 200 mg comes into play. Doctors are prescribing Celebrex 200 mg more and more as a treatment to the pain of osteoarthritis. Celebrex 200mg is also safe and economical. Celebrex 200 mg not only controls the pain but also inflammation.
There is no single treatment of osteoarthritis but a multifaceted approach is followed which involves changing the life style, cutting down weight, taking some supplements that help improve healing, taking pain killers and anti inflammatory medications( celebrex 200 mg ) . If all else fails then a more aggressive approach is the joint replacement surgery which requires great expertise, massive expenses and not a good prognosis over time.
Celecoxib ( celebrex 200 mg )is an anti inflammatory drug that holds or reduces the process of inflammation, thereby preventing further damage to the joint and reducing pain. This drug ( celebrex 200 mg ) acts on an enzyme in our body called the cyclooxygenase 2 or COX-2 and not on cyclooxygenase 1 or COX-1.
The cyclooxygenase produce prostaglandins which are required for a normal immune response. By blocking the synthesis of these prostaglandins, the process of inflammation can be easily controlled. Selective action on type 2 cyclooxygenase ensure that only the pathological inflammation is controlled and the protective role of the immune system that is mainly controlled by type 1 cyclooxygenase is not disturbed. A good example of type 1 mediated system is the role that the immune system plays in the stomach. It synthesizes or manufactures prostaglandins in the wall of stomach that helps maintain a layer of protective mucosa that lines this wall. This mucosa is essential for the prevention of gastric ulcers. Most of the non selective anti inflammatory drugs blocks this type 1 enzyme as well and is can lead to gastric ulcers.
Celecoxib ( celebrex 200 mg ) being a selective COX-2 blocker can be used to control inflammation and pain of osteoarthritis without the risk of developing gastric ulcers. Celecoxib is available in market as Celebrex 200mg tablet. It is usually very effective in controlled the pain and inflammation of osteoarthritis with comparatively very few adverse effects. Celebrex 200mg is usually prescribed to patients of osteoarthritis as bid or qid dose i.e. it has to be taken two to four times a day. Celebrex 200 mg does not cause gastric irritation. Celebrex 200 mg can be taken without meal.